Submit Manuscript  

Article Details


One-Pot Approach to 4-Vinyl-1,2,3-Triazoles by Cycloaddition of Azides with Propargyl Alcohols Catalyzed by Cu(I)/Ru(III)/TFA

[ Vol. 9 , Issue. 6 ]

Author(s):

Ji Su and Ruimao Hua   Pages 898 - 902 ( 5 )

Abstract:


An efficient and regioselective one-pot direct synthesis of 4-vinyl-1,2,3-triazoles via cycloaddition of azides with propargyl alcohols and dehydration catalyzed by a CuCl/RuCl3ยท3H2O bimetallic catalysts in the presence of TFA (Trifluoroacetic acid) is developed.

Keywords:

Azides, Cuprous chloride, Propargyl alcohols, Ruthenium trichloride hydrate, 4-Vinyl-1, 2, 3-triazoles, Trifluoroacetic acid.

Affiliation:

Department of Chemistry, Tsinghua University, Key Laboratory of Organic Optoelectronics & Molecular Engineering of Ministry of Education, Beijing 100084, China.



Read Full-Text article