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Palladium-Catalyzed Cycloaddition of 1,3-Butadiynes with Water: An Alternative Efficient Catalytic System for Atom-Economic Synthesis of 2,5-Disubstituted Furans

[ Vol. 10 , Issue. 1 ]


Qingwei Zheng, Ruimao Hua and Tao Yin   Pages 161 - 164 ( 4 )


An efficient Pd(PPh3)4/2,5-norbornadiene-catalyzed cycloaddition of 1,4-disubstituted 1,3-butadiynes with H2O under basic conditions for straightforward and simple synthesis of 2,5-disubstituted furans is described.


Cycloaddition, 1, 3-butadiynes, furan derivative, palladium, water


Department of Chemistry, Tsinghua University, Key Laboratory of Organic Optoelectronics & Molecular Engineering of Ministry of Education, Beijing 100084, China.

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