Abhishek Santra and Anup Kumar Misra Pages 178 - 182 ( 5 )
A concise chemical synthesis of the common tetrasaccharide corresponding to the O-antigen of enteroinvasive Escherichia coli O143 and Shigella boydii type 8 has been achieved in excellent yield. Application of [2+2] block glycosylation and late stage oxidation of primary hydroxyl groups to the carboxylic groups are notable features in the synthetic strategy.
Escherichia coli, Shigella boydii, O-antigen, tetrasaccharide, dysentery
Bose Institute, Division of Molecular Medicine, P-1/12, C.I.T. Scheme VII M, Kolkata 700054, India.