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Article Details


Applications of Barbier Type Reactions in Carbohydrate Chemistry

[ Vol. 10 , Issue. 2 ]

Author(s):

Raquel G. Soengas and Amalia M. Estevez   Pages 183 - 209 ( 27 )

Abstract:


Stereocontrolled formation of C–C bonds in polyfunctionalized carbohydrate derivatives, which are crucial synthetic intermediates, is sometimes very challenging. The application of low valent organometallic reagents for C–C bond formation in carbohydrate chemistry has recently attracted a great deal of attention, largely due to the mild reaction conditions required. We present here an overview of the application of different reductive C–C bond forming reactions in carbohydrate chemistry.

Keywords:

C–C bond formation, barbier, reformatsky, pinacol coupling, single electron transfer (SET), carbohydrates

Affiliation:

Centro Singular de Investigacion en Quimica Biologica y Materiales Moleculares, Campus Vida, Universidad de Santiago de Compostela, Jenaro de la Fuente s/n, 15782, Santiago de Compostela, Spain.



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