Anna Kuz nik, Roman Mazurkiewicz and Nikodem Ku znik Pages 411 - 424 ( 14 )
The synthesis of α,β-dehydro-α-aminophosphonic and α,β -dehydro-α-aminophosphinic acid derivatives is discussed. The most important synthetic pathways to the above-mentioned compounds have been divided into four groups depending on the type of bond formed as the last one. The configuration at the C=C double bond can be established based on the specific coupling constants 3JHP and 3JCP for the appropriate Z- and E-stereoisomers. The application of α,β -dehydro-α -aminophosphonates and α,β -dehydro- α- aminophosphinates, particularly in the enantioselective catalytic hydrogenation, is also discussed.
α -aminophosphinic acids, α -aminophosphonic acids, asymmetric catalytic hydrogenation, α , β -dehydro-α -aminophosphinates, α, β -dehydro-α -aminophosphonates, Michaelis-Arbuzov reaction, Wadsworth-Emmons reaction.
Department of Organic and Bioorganic Chemistry and Biotechnology, Silesian University of Technology, B. Krzywoustego 4, PL 44-100 Gliwice, Poland.