Ramon Rios, SimonaHybelbauerova, Ivana C sa rova and Jan Vesel y Pages 467 - 471 ( 5 )
A highly enantioselectiveorganocatalyticnitromethylphenylsulfone addition to aliphatic α,β- unsaturated aldehydes is reported. The reaction is catalyzed by simple and commercially available secondary amines, affording the cyclic compounds in moderate yields, good diastereoselectivities and excellent enantioselectivities.
Cascade reaction, enantioselective, organocatalysis, asymmetric synthesis, secondary amine, cyclization.
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