Orazio A. Attanasi, Luca Bianchi, Maurizio D’Auria, Fabio Mantellini and Rocco Racioppi Pages 631 - 639 ( 9 )
1,2-Diaza-1,3-dienes bearing electron-withdrawing groups react with electron-poor alkenes by means of an uncommon aza- Diels-Alder reaction furnishing novel tetrahydropyridazines with high regio- and stereoselectivity. Conducting these cycloadditions in solvent free conditions under thermal conditions the reaction times are significantly reduced, the yields are improved and the stereoselectivity remained unchanged.
1, 2-Diaza-1, 3-dienes, Electron- poor alkenes, Aza-Diels-Alder, Solvent free conditions, DFT calculations.
Istituto di Chimica Organica, Universita degli Studi di Urbino “Carlo Bo”, Via I Maggetti, 24, 61029 Urbino (PU), Italy.