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One-Pot Synthesis of 2,4,6-Triarylpyridines by the Oxidative Cyclocondensation of Benzaldehydes, Aromatic Alkynes and Ammonium Bifluoride

[ Vol. 10 , Issue. 4 ]


Ping Wang, Ruimao Hua and Chao-Jun Li   Pages 655 - 660 ( 6 )


An efficient and one-pot synthesis of 2,4,6-triarylpyridines by palladium-catalyzed cyclocondensation of benzaldehydes, terminal aromatic alkynes and ammonium bifluoride in the presence of tert-butyl peroxide (TBP) as oxidant is developed.


Aromatic alkyne, ammonium bifluoride; benzaldehyde, cyclocondensation, triarylpyridines.


Department of Chemistry, Tsinghua University, Beijing 100084, China.

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