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A Facile and Quick Synthesis of 9-aryl-substituted-acridines Mediated by DMP

[ Vol. 10 , Issue. 6 ]


George Bratulescu   Pages 947 - 950 ( 4 )


An unexpected three components reaction was developed for acridine synthesis in solvent free medium. The reaction is carried out with commercial reagents using of microwaves in a heterogeneous medium in presence of zinc chloride and 2,2-dimethoxypropane (DMP) as water scavenger. Principal advantages of the method are: short time, high yields and easy work-up.


Aromatic acids, acridine, bernthsen reaction, diphenylamine, DMP, water scavenger.


University of Craiova, Faculty of Chemistry, 13 A.I. Cuza, 200585 Craiova, Romania.

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