George Bratulescu Pages 947 - 950 ( 4 )
An unexpected three components reaction was developed for acridine synthesis in solvent free medium. The reaction is carried out with commercial reagents using of microwaves in a heterogeneous medium in presence of zinc chloride and 2,2-dimethoxypropane (DMP) as water scavenger. Principal advantages of the method are: short time, high yields and easy work-up.
Aromatic acids, acridine, bernthsen reaction, diphenylamine, DMP, water scavenger.
University of Craiova, Faculty of Chemistry, 13 A.I. Cuza, 200585 Craiova, Romania.