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Synthesis of Allosamidin and its Analogues

[ Vol. 11 , Issue. 5 ]

Author(s):

Gangliang Huang and Qilin Tang   Pages 696 - 700 ( 5 )

Abstract:


The pseudo-trisaccharide allosamidin 1 is a potent inhibitor of all family 18 chitinases, and it is confirmed to have biological activities against insects and fungi. The solid/liquid phase syntheses of allosamidin 1 and its analogues have been developed in recent years, and these compounds can be obtained by iterative glycosylation reactions, catalytic hydrogenation, acetylation, deacetylation, or photolysis, respectively.

Keywords:

Allosamidin, analogues, recent development, synthesis.

Affiliation:

Key Lab of Green Synthesis and Applications, College of Chemistry, Chongqing Normal University, Chongqing, 401331, China.

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