Pavel Drabina, Lydie Harmand and Milos Sedlak Pages 879 - 888 ( 10 )
This present mini-review summarizes the recently published development and trends concerning catalysts based on immobilized complexes of transition metals which are designated for asymmetric Henry reaction. The paper presents examples of originally homogeneous catalysts which were anchored to organic carriers (such as dendrimers, polymers) or inorganic materials. The catalysts based on organic carriers are classified and discussed in accordance to their solubility in reaction medium. In the case of inorganic materials, the discussed catalysts were anchored to different types of surface of micro- and nano-particles. The discussion concerns the effect of immobilization of catalysts on the overall reaction yield, enantioselectivity, possible recycling, and the effect of recycling on the abovementioned parameters.
Enantioselective catalysis, Henry reaction, nitroaldol reaction, recyclable catalysts, solid supported catalyst, transition metal complexes.
Institute of Organic Chemistry and Technology, Faculty of Chemical Technology, University of Pardubice, Studentska 573, 532 10 Pardubice, Czech Republic.