Submit Manuscript  

Article Details

Multicomponent Reactions in Water Medium Catalyzed by Zn-VCO3 Hydrotalcite: A Greener and Efficient Approach for the Synthesis of Multifunctionalized Benzenes

[ Vol. 12 , Issue. 2 ]


Ramakanth Pagadala, Suresh Maddila, Surjyakanta Rana and Sreekantha B. Jonnalagadda   Pages 163 - 167 ( 5 )


A highly efficient method for synthesis of multifunctionalized benzenes by one-pot multicomponent condensation between malononitrile, substituted aldehyde and cycloheptanone catalyzed by Zn-VCO3 hydrotalcite is reported. With water as solvent, this green chemistry reaction entails mild conditions. It is atom-efficient, high-yielding and pertinent to an extensive variety of multicomponent reactions.


Green chemistry, multicomponent reaction, multifunctionalized benzenes, reusable catalyst, water as a solvent, Zn-VCO3 hydrotalcite.


School of Chemistry & Physics, University of KwaZulu-Natal, Westville Campus, Chiltern Hills, Durban-4000, South Africa.

Graphical Abstract:

Read Full-Text article