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Drug Likeness and Selective Functionalization of Quinoxalines

[ Vol. 12 , Issue. 6 ]


Samuel R. A. Ferreira, Marcia S. F. Franco, Evelyn M. L. P. Diniz, Flavio da Silva Emery and Giuliano Cesar Clososki   Pages 714 - 729 ( 16 )


In recent years, the pharmacological potential of quinoxalines has received vast interest due to its many applications. This review centers on a critical overview of chemical diversity and physicochemical properties of bioactive quinoxaline libraries. In addition, recent strategies for obtaining structurally diverse quinoxalines using highly selective processes will be discussed.


Quinoxaline, heterocycles, C-H activation, drug-likeness, organometallics.


Faculdade de Ciências Farmacêuticas de Ribeirão Preto; Universidade de São Paulo, Av. do Café S/N, Ribeirão Preto – SP 14040-903, Brazil.

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