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Recent Advances in the Asymmetric Claisen Rearrangement Promoted by Chiral Organometallic Lewis Acids or Organic Bronsted-Lowry Acids

[ Vol. 12 , Issue. 6 ]

Author(s):

Tiago Costa Alves Fontoura Rodrigues, Wender Alves Silva and Angelo Henrique Lira Machado   Pages 795 - 805 ( 11 )

Abstract:


The Claisen rearrangement, an important C–C bond forming reaction, has been used enormously for many decades in the synthesis of important class of compounds. This review covers developments in this rearrangement since 2008, discusses important aspects about the asymmetric Claisen rearrangement catalyzed by chiral organometallic Lewis acids or organic Brønsted-Lowry acids.

Keywords:

[3, 3] sigmatropic, organocatalysis, chiral Lewis acids, claisen rearrangement, asymmetric rearrangement, catalysis.

Affiliation:

University of Brasilia, Institute of Chemistry P.O box 4408, Brasilia, Brazil.

Graphical Abstract:



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