Amna M. Abdella, Ahmed H. M. Elwahy and Ismail A. Abdelhamid Pages 601 - 610 ( 10 )
An efficient and convenient route for synthesis of novel bis 4H-chromene-3- carbonitrile derivatives is reported. The synthetic pathway involves one pot, multi-component reaction of bis-aldehydes, malononitrile, and dimedone in the presence of a catalytic amount of piperidine. A stepwise approach for the synthesis of the target compounds was also investigated.
Bis-aldehydes, bis-arylidenemalononitriles, multicomponent reactions, Bis-4H-chromene-3-carbonitriles.
Chemistry Department, Faculty of Science, Cairo University, Giza-Egypt.