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Suzuki-Miyaura Cross-Coupling Reaction Catalyzed by Supported Palladium Under Microwave Irradiation

[ Vol. 14 , Issue. 3 ]

Author(s):

Qing Han Li, Yong Ding, Gang Zhang, Zhen Zhang and Song Mo   Pages 462 - 476 ( 15 )

Abstract:


Organic synthesis efficiency can take considerable advantage from microwave heating. Compared to conventional heating, it allows to improve the reactions speed and yield through an energy-efficient, clean, and easy-to-use processing tool. Transition-metal catalyzed cross-coupling reactions and in particular the Suzuki- Miyaura cross-coupling is powerful and widely used tool for the formation of carbon-carbon bonds. Crosscoupling reactions are of large interest for the bonding of a broad range of functional groups, in particular biaryl groups, allowing for a strong stereoselectivity. In this paper, recent research results concerning the application of microwave heating in Suzuki-Miyaura cross-coupling reactions are reviewed with particular emphasis on reactions involving supported Pd as a catalyst.

Keywords:

Microwave chemistry, Suzuki-Miyaura reaction, supported palladium, C-C bond formation, organoboron compounds, crosscoupling.

Affiliation:

College of Chemistry and Environmental Protection Engineering, Southwest University for Nationalities, P.O. Box: 610041, Chengdu

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