Edgars Abele, Sergey Belyakov, Tatjana Beresneva, Lena Golomba and Ramona Abele Pages 883 - 887 ( 5 )
Novel palladium-catalyzed cascade reaction of 2-methylindoles with 2- iodobenzyl bromide in the system Pd(OAc)2 / Xantphos / t-BuOK / toluene leading to indole- fused tricyclo[7,3,1,02,7] trideca-2(7),3,5-triene ring system was presented. Palladium catalyzed reaction of 2-methylindoles with 6-bromo-5-bromomethylbenzo[1,3] dioxole leads to 3,3-bis(6-bromobenzo[1,3]dioxol-5-ylmethyl)-2-methyl-3H-indoles.
Palladium catalysis, 2-methylindoles, potassium t-butoxide, 2-iodobenzyl bromide, tricyclo[7, 3, 1, 02, 7]trideca-2(7), 3, 5-trienes.
Latvian Institute of Organic Synthesis, Aizkraukles 21, Riga, Latvia.