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The Utility of Hydrazonoyl Halides in the Synthesis of Bioactive Heterocyclic Compounds

[ Vol. 14 , Issue. 3 ]

Author(s):

Thoraya A. Farghaly, Magda A. Abdallah and Huda K. Mahmoud   Pages 430 - 461 ( 32 )

Abstract:


This review deals with the utility of hydrazonoyl halides in synthesis of bioactive heterocylic compounds such as pyrazoles, triazoles and pyrimidines which showed wide range of biological activities. We discussed here the synthesis of heterocyclic ring system derived from hydrazonoyl halides and their significant biological properties as for example, antitumor, antimicrobial, analgesic, anti-inflammatory, anti-H1N1 and anti HCV activity.

Keywords:

Hydrazonoyl halides, heterocycles, anticancer, antimicrobial, anti-inflammatory.

Affiliation:

Department of Chemistry, Faculty of Science, University of Cairo, Giza 12613, Department of Chemistry, Faculty of Science, University of Cairo, Giza 12613, Department of Chemistry, Faculty of Science, University of Cairo, Giza 12613

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