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The Diels-Alder Reaction and its Applications in the Total Synthesis of Natural Products

[ Vol. 13 , Issue. 6 ]


Hongyu Ran and Gangliang Huang   Pages 847 - 860 ( 14 )


The Diels-Alder (DA) reaction has been applied to the total synthesis of natural products. It can get good yields because of high stereoselectivity and regioselectivity. Herein, the DA reaction catalyzed by Lewis acids was introduced, and some total syntheses of natural products from 2013 to 2015 using DA reaction were also illustrated and analyzed.


Diels-Alder reaction, Total synthesis, Applications.


College of Chemistry, Chongqing Normal University, Chongqing, 401331, China.

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