Marwa A. M. Sh. El-Sharief*, Reem A. K. Al-Harbi, Samir Y. Abbas*, Eman W. El-Gammal and Ahmed M. Sh. El-Sharief Pages 1 - 8 ( 8 )
Aim and Objective: It was of interest to synthesizing some new imidazolidineiminothione derivatives with different halogenated and alkylated aromatic substituent at N-(1) and N-(3) and evaluation of their antibacterial and antifungal properties.
Materials and Methods: New imidazolidineiminothione derivatives were synthesized through the reaction of different halogenated and alkylated N-arylcyanothioformamide derivatives with halogenated and alkylated aryl isocyanates.
Results: The imidazolidineiminothione derivatives were obtained in high yields with excellent purity. The activity of imidazolidineiminothione derivatives as antibacterial and antifungal agents was studied. Some of imidazolidineiminothione derivatives displayed significant antibacterial and antifungal activities.
N-Arylcyanothioformamides, Imidazolidineiminothiones, Antibacterial, antifungal activities, imidazole derivatives, heterocyclic compounds.
Applied Organic Chemistry Department, National Research Centre, Cairo, Department of Chemistry, Faculty of Science, Taibah University, Almadinah Almunawarrah, Organometallic and Organometalloid Chemistry Department, National Research Centre, Cairo, Department of Chemistry of Natural and Microbial Products, National Research Centre, Cairo, Chemistry Department, Faculty of Science, Al-Azhar University (Boys), Cairo