Jasmin Sultana and Diganta Sarma* Pages 65 - 72 ( 8 )
Introduction: An effective Cu-complex, [Cu(NH3)4SO4 • H2O] was prepared conveniently from the inexpensive and easily available starting reagents in a simple route.
Materials and Methods: Excellent reactivity of the catalyst was observed towards two competent clickcycloadditions: (a) oxidative cycloaddition of azides with electron-poor olefins and (b) one-pot cycloaddition of alkynes with boronic acid and sodium azide under “click-appropriate” conditions.
Results: No external oxidant, short reaction time, high product yield, wide substrate scope, and aqueous solvent media make the azide-olefin cycloaddition approach a greener route in contrast to the reported methods.
Conclusion: The newly developed mild, green, and rapid three-component strategy shows product diversity with superb yields at room temperature by reducing the synthetic process time and using only 1 mol % of the synthesized copper complex.
Ammoniated Cu-complex, OAOC, boronic acid, aqueous media, regioselective, 1, 2, 3-triazole.
Department of Chemistry, Dibrugarh University, Dibrugarh, Department of Chemistry, Dibrugarh University, Dibrugarh