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Applications of the Dess-Martin Oxidation in Total Synthesis of Natural Products

[ Vol. 18 , Issue. 2 ]

Author(s):

Majid M. Heravi*, Tayebe Momeni, Vahideh Zadsirjan* and Leila Mohammadi   Pages 125 - 196 ( 72 )

Abstract:


Dess–Martin periodinane (DMP), a commercially available chemical, is frequently utilized as a mild oxidative agent for the selective oxidation of primary and secondary alcohols to their corresponding aldehydes and ketones, respectively. DMP shows several merits over other common oxidative agents such as chromiumand DMSO-based oxidants; thus, it is habitually employed in the total synthesis of natural products. In this review, we try to underscore the applications of DMP as an effective oxidant in an appropriate step (steps) in the multi-step total synthesis of natural products.

Keywords:

Dess-Martin periodinane, DMP, oxidation, total synthesis, natural products, oxidation, alcohols, aldehydes, ketones.

Affiliation:

Department of Chemistry, School of Science, Alzahra University, P.O. Box 1993891176, Vanak, Tehran, Department of Chemistry, School of Science, Alzahra University, P.O. Box 1993891176, Vanak, Tehran, Department of Chemistry, School of Science, Alzahra University, P.O. Box 1993891176, Vanak, Tehran, Department of Chemistry, School of Science, Alzahra University, P.O. Box 1993891176, Vanak, Tehran

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