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Synthetic and Biological Attributes of Pyrimidine Derivatives: A Recent update

Author(s):

Meenu Devi, Shivangi Jaiswal, Sonika Jain, Navjeet Kaur and Jaya Dwivedi*  

Abstract:


Nitrogen-containing heterocycles attract the attention of chemists due to their multifarious activities. Amongst all, pyrimidine plays a central role and exhibits a broad spectrum of biological activities. Literature is replete with the various aspects of synthetic development in pyrimidine chemistry for a wide array of applications. It aroused our interest to compile various novel and efficient synthetic approaches towards the synthesis of pyrimidine and its derivatives. Pyrimidine derivatives are broadly useful as therapeutic agents, owing to their high degree of structural diversity. They have been recorded to possess a diverse range of therapeutic activities, viz. anticancer, anti-inflammatory, anti-HIV etc.

Keywords:

Heterocycles, pyrimidine, synthesis, coupling reactions, green methods, anticancer

Affiliation:

Department of Chemistry, Banasthali Vidyapith,, Banasthali-304022, Department of Chemistry, Banasthali Vidyapith,, Banasthali-304022, Department of Chemistry, Banasthali Vidyapith,, Banasthali-304022, Department of Chemistry, Banasthali Vidyapith,, Banasthali-304022, Department of Chemistry, Banasthali Vidyapith,, Banasthali-304022



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