Estibaliz Sansinenea and Aurelio Ortiz* Pages 1 - 18 ( 18 )
Background: The total syntheses of complex natural products have evolved to include new methodologies to save time, simplifying the form to achieve these natural compounds.
Objective: In this review, we have described the asymmetric synthesis of different natural products and biologically active compounds of the last ten years until the current day.
Results: An asymmetric organocatalytic reaction is a key to generate stereoselectively the main structure with the required stereochemistry.
Conclusion: Even more remarkable, the organocatalytic cascade reactions, which are carried out with high stereoselectivity, as well as a possible approximation of the organocatalysts activation with sub-strates are also described.
Organocatalysis, organocatalytic process, organocatalytic cascade reactions, asymmetric synthesis, natural products, stereoselec-tivity, catalyst.
Facultad de Ciencias Químicas, Benemérita Universidad Autónoma de Puebla, Puebla, Facultad de Ciencias Químicas, Benemérita Universidad Autónoma de Puebla, Puebla