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Strategies in Synthetic Radical Organic Chemistry. Recent Advances on Cyclization and SRN1 Reactions

[ Vol. 3 , Issue. 2 ]

Author(s):

Roberto A. Rossi and Alicia B. Penenory   Pages 121 - 158 ( 38 )

Abstract:


Radical ring closure reactions by intramolecular addition of a radical to a tethered double bond afford a new cyclized radical intermediate that can be reduced, or further react with different reagents to yield substituted-cyclic compounds. The applications of SRN1 reactions are broad in scope, encompassing the utilization of poorly reactive substrates. We undertake a compilation to cover recent literature of these reactions and their synthetic applications.

Keywords:

Ring closure, reduction, SRN1, radicals, radical anions, electron transfer

Affiliation:

INFIQC, Departamentode Quimica Organica, Facultad de Ciencias Quimicas, UniversidadNacional de Cordoba, 5000 Cordoba, Argentina.



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