Submit Manuscript  

Article Details


Enzymatic Biosynthesis of Oligosaccharides and Glycoconjugates

[ Vol. 3 , Issue. 2 ]

Author(s):

Jing Song, Houcheng Zhang, Lei Li, Zishu Bi, Min Chen, Wei Wang, Qingjia Yao, Hongjie Guo, Min Tian, Hanfen Li, Wen Yi and Peng George Wang   Pages 159 - 168 ( 10 )

Abstract:


Natural carbohydrates have complex structures including many kinds of monosaccharide units, which are very difficult and costly to generate by chemical synthetic approaches. Over the years, enzymatic approaches have been gaining popularity for the synthesis of oligosaccharides and glycoconjugates, and it is becoming increasingly feasible to produce complex carbohydrates in large scale, following enzymatic biosynthetic pathways.

Keywords:

Glycosidases, sugar nucleotides, glycosyl donors, UDP, –, N -acetylglucosamine, Glycosyltransferases

Affiliation:

Department ofBiochemistry, The Ohio State University, Columbus, OH 43210, USA.



Read Full-Text article