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Synthesis of the C-13 Side-Chain of Taxol

[ Vol. 4 , Issue. 2 ]

Author(s):

Jagat C. Borah, Joshodeep Boruwa and Nabin C. Barua   Pages 175 - 199 ( 25 )

Abstract:


This review covers different synthetic routes to the C-13 side-chain of taxol the most potent antimicrotubule agent first isolated from Texus bravifolia and later on from several other species of Taxus. The different approaches reported for the syntheses of the C-13 side-chain of taxol are catagorized on the synthetic strategies applied.

Keywords:

Taxol, 10-DAB, C-13 side-chain, total synthesis, antimicotubule

Affiliation:

Natural Products Chemistry Division, Regional Research Laboratory (CSIR), Jorhat-785 006, Assam,India.



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