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Some Applications of Ultrasound Irradiation in Organic Synthesis

[ Vol. 2 , Issue. 3 ]


Ji-Tai Li, Shu-Xiang Wang, Guo-Feng Chen and Tong-Shuang Li   Pages 415 - 436 ( 22 )


The chemical applications of ultrasound, “sonochemistry”, have become an exciting new field of research during the past decade. Scientists now know that the chemical effects of ultrasound are diverse and include substantial improvements in both stoichiometric and catalytic chemical reactions. In some cases, ultrasonic irradiation can increase reactivities by nearly a million fold. The chemical effects of ultrasound fall into homogeneous sonochemistry of liquids, heterogeneous sonochemistry of liquid-liquid or liquid-solid systems. In this paper, some recent applications of ultrasound in organic synthesis, such as, Knoevenagel condensation, Claisen-Schmidt condensation, Michael addition, Pinacol coupling reaction, Bucherer-Bergs reaction and Biginelli reaction, are reviewed.


sonochemistry, knoevenagel condensation, cyanocinnamates, arylmethylenemalonitrile, claisen-schmidt condensation, chalcones, michael addition, pinacol coupling reaction


College of Chemistry and Environmental Science, Hebei University; Key Laboratory of AnalyticalScience and Technology, Hebei Province, Baoding 071002, P.R. China.

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