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Recent Developments on the Synthesis of (-)-Swainsonine and Analogues

[ Vol. 2 , Issue. 1 ]

Author(s):

Stephen G. Pyne   Pages 39 - 57 ( 19 )

Abstract:


This paper reviews the latest developments in the synthesis of swainsonine and its analogues since the first review in this area by Nemr which covered the literature up to 1999 (Nemr, A. E. Tetrahedron 2000, 56, 8579- 8629).

Keywords:

swainsonine, ring-closing metathesis, ruthenium catalysed rearrangement, epoxide, dihydroxylation, indolizine, pyrrolidine, meso compounds, asymmetric desymmetrization, enzyme kinetic resolution

Affiliation:

Department of Chemistry,University of Wollongong, Wollongong, NSW, 2522, Australia.



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