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Developments in the Synthesis of Organometallic Amino Acids and Analogues

[ Vol. 7 , Issue. 3 ]

Author(s):

Poulami Jana, Sibaprasad Maity and Debasish Haldar   Pages 224 - 234 ( 11 )

Abstract:


Structure and function of synthetic amino acids with side chain metal complexes have particular importance for extending our understanding of organometallic compounds under physiological conditions and mimic protein folding and stabilization. Chemists are now designing biomimetic organo-metallic amino acids that can form both secondary and tertiary structures. An overview of the design and synthesis of non-proteinogenic amino acids containing metal ions in the side chain is discussed.

Keywords:

Amino acid analogues, side chain metal complex, synthesis, structure

Affiliation:

Department of Chemical Sciences, Indian Institute of Science Education and Research–Kolkata, Mohanpur, West Bengal- 741252, India.



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