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(Masked)serinols: Molecules, Biomolecules, Building-Blocks, Supramolecules.Part (I): Syntheses Based on Serinols Reactivity with Carbonyl Electrophiles

[ Vol. 7 , Issue. 2 ]

Author(s):

Mircea Darabantu   Pages 120 - 152 ( 33 )

Abstract:


Since the period of the 1940s, 2-aminopropane-1,3-diol (“serinol”) and its commercial C-substituted analogous are a popular motif in organic compounds covering almost all facets of organic synthesis. This first part of the review deals mainly with the nowadays approaches focused on serinolsreactivity with carbonyl electrophiles (aldehydes and ketones) as well as its applications.

Keywords:

2-aminopropane-1,3-diols, ring-chain tautomerism, 1,3-oxazolidines, 3,7-dioxa-1-azabicyclo[3.3.0]octanes, 5-amino-1,3-dioxanes, asymmetric synthesis

Affiliation:

“Babes-Bolyai” University, Department of Organic Chemistry, 11 Arany Janos str., 400 028 Cluj-Napoca, Romania.



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