Submit Manuscript  

Article Details

Cu-Mediated Organic Transformations in Water

[ Vol. 9 , Issue. 1 ]


Fabio Marinelli   Pages 2 - 16 ( 15 )


Cu-based catalysts represent a powerful tool for a variety of synthetic transformations, including arylation of nucleophiles, alkyne coupling, dipolar cycloadditions, Diels-Alder reactions, oxidations, condensations and enantioselective reactions. The use of water as reaction medium for these procedures is currently emerging as a very active research field. The present Review focuses on the more synthetically useful “on water” Cu-mediated processes, in which organic co-solvents are absent (or present in negligible amount), and covers the literature until the end of 2009.


Copper catalysis, Water, Ullman reaction, Cycloadditions, Oxidations, Enantioselective reactions, dipolar cycloadditions, 2-Dimethylaminoethanol, 2,2'-Biquinoline-4,4'-dicarboxylic acid dipotassium salt, Ethylenediamine, Polyethylene glycol, N,N,N',N'Tetramethylethylenediamine


Dipartimento di Chimica, Ingegneria Chimica e Materiali, Universita dell'Aquila, via Vetoio, I-67100 L'Aquila, Italy.

Read Full-Text article