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An Efficient Copper-Catalyzed Cyclocondensation of Anilines with Propargyl Alcohols Approach to 1,2-Dihydroquinolines

[ Vol. 9 , Issue. 2 ]

Author(s):

Ji Su, Jia Ju and Ruimao Hua   Pages 273 - 277 ( 5 )

Abstract:


The cyclocondensation of anilines with propargyl alcohols in the presence of catalytic amount of CuCl and CuCl2·2H2O to afford 1,2-dihydroquinolines with high atom-efficiency in moderate to good yields is developed.

Keywords:

Anilines, Copper-catalyzed, Cyclocondensation, 1, 2-Dihydroquinoline, Propargyl alcohols

Affiliation:

Department of Chemistry, Tsinghua University, Key Laboratory of Organic Optoelectronics&Molecular Engineering of Ministry of Education, Beijing 100084, China.



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