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Stereoselective Synthesis of α-Aminophosphonic Acids Analogs of the 20 Proteinogenic α-Amino Acids

[ Vol. 9 , Issue. 3 ]

Author(s):

Mario Ordonez, Jose Luis Viveros-Ceballos, Carlos Cativiela and Alicia Arizpe   Pages 310 - 341 ( 32 )

Abstract:


This review describes the synthesis, biological interest and importance of the α-aminophosphonic acids analogs of the 20 proteinogenic α-amino acids. Special attention is devoted to those stereoselective procedures that allow the synthesis of the required compounds in enantiomerically pure form.

Keywords:

α-Aminophosphonic acids, α-aminophosphonates, α-amino acids, stereoselective synthesis, biological activity, resolution

Affiliation:

Centro de Investigaciones Quimicas, Universidad Autonoma del Estado de Morelos, 62209 Cuernavaca, Morelos, Mexico.



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